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Brain Informatics
Fig. 2 | Brain Informatics

Fig. 2

From: Quantitative investigation of memory recall performance of a computational microcircuit model of the hippocampus

Fig. 2

(Left) Recall microcircuit model of region CA1 of the hippocampus and (right) CA1-PC model with one excitatory (CA3) and six inhibitory (BSC) synaptic contacts on its dendrites. EC: entorhinal cortical input; CA3: Schaffer collateral input; AAC: axo-axonic cell; BC: basket cell; BSC: bistratified cell; OLM: oriens lacunosum-moleculare cell; SLM: stratum lacunosum-moleculare; SR: stratum radiatum; SP: stratum pyramidale; SO: stratum oriens. During recall, only PCs, BSC, and OLM cell are active. AAC and BCs are inactive due to strong medial septum inhibition. BSC and PC are driven on their SR dendrites by a strong CA3 excitatory input, which represented the contextual information. EC input is disconnected from the network, which thus has no effect on it. Red circles on PC dendrites represent loaded synapses, whereas black circles on PC dendrites represent unloaded synapses

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