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Table 3 Synaptic parameters in healthy condition

From: The onset of motor learning impairments in Parkinson’s disease: a computational investigation

Weight

Value (nS)

Model

\(w^{\text {input}}_{\text {striatum-Go}}\)

U(0.02, 0.12)

exc

\(w^{\text {input}}_{\text {striatum-NoGo}}\)

U(0.02, 0.12)

exc

\(w^{\text {striatum}}_{\text {striatum}}\)

U(0.01, 0.04)

inh

\(w^{\text {PMC}}_{\text {striatum-Go}}\)

U(0.4, 0.5)

exc

\(w^{\text {PMC}}_{\text {striatum-NoGo}}\)

1.0

exc

\(w^{\text {SNc}}_{\text {striatum-Go}}\)

0.15

exc

\(w^{\text {SNc}}_{\text {striatum-NoGo}}\)

0.3

inh

\(w^{\text {striatum-Go}}_{\text {GPi}}\)

1.5

inh

\(w^{\text {GPe}}_{\text {GPi}}\)

1.0

inh

\(w^{\text {STN}}_{\text {GPi}}\)

6.0

exc

\(w^{\text {striatum-NoGo}}_{\text {GPe}}\)

1.0

inh

\(w^{\text {GPe}}_{\text {STN}}\)

0.35

inh

\(w^{\text {PMC}}_{\text {STN}}\)

U(0.45, 0.85)

exc

\(w^{\text {input}}_{\text {PMC}}\)

U(0.0045, 0.055)

exc

\(w^{\text {thalamus}}_{\text {PMC}}\)

2.0

exc

\(w^{\text {PMC}}_{\text {thalamus}}\)

1.5

exc

\(w^{\text {GPi}}_{\text {thalamus}}\)

1.0

inh

\(w^{\text {PMC}}_{\text {M1}}\)

2.0

exc