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Table 1 Biological ontologies used to generate CeN–CAM models

From: Semantic representation of neural circuit knowledge in Caenorhabditis elegans

GO–CAM element

Ontology

Example

Molecular activity

GO Molecular Function

serotonin receptor activity (GO: 0099589)

Biological process

GO Biological Process

membrane depolarization (GO: 0051899)

Location

GO Cellular Component

cytosol (GO: 0005829)

Cell

WormBase Anatomy Ontology

HSN (WBbt: 0006830)

Active entity (gene/gene product)

WormBase

tph-1 (WBGene00006600)

Chemical inputs

Chemical Entities of Biological Interest (ChEBI)

dioxygen (CHEBI: 15379)

Relations arrows

Relations Ontology (RO), Basic Formal Ontology (BFO)

occurs in (RO_0002479)

Evidence codes

Evidence and Conclusions Ontology (ECO)

optogenetic evidence used in manual assertion (ECO: 0006033)

Environmental conditions

Phenotype and Trait Ontology (PATO) Environmental Conditions, Treatments and Exposure Ontology (ECTO)

increased duration (PATO_0000498)