Fig. 1

Standard GO annotations and GO–CAMs. A Standard GO annotations link genes to GO Molecular Functions, GO Biological processes or GO Cellular Component terms. B Partial GO–CAM of canonical glycolysis. Gene Ontology–Causal Activity Models (GO–CAMs) arrange GO annotations into structured models of biological processes by causally linking GO Molecular Functions that make up a process. Edges represent relations which may connect nodes according to the GO–CAM data model