Fig. 5

Relationship between dynamic synaptic and functional connectivity. A Dynamic connectivity for 3 example synapses, T = 10 min. Top left: ground truth dynamics of synaptic weights (DSC). Top right: transfer entropy DFC. Bottom left: HOTE DFC. Bottom right: cross-covariance DFC. B Distribution of the across-time correlation coefficients between DSC and DFC, T = 10 min. Left: Transfer entropy. Middle: HOTE. Right: cross-covariance. Colored dots show where the synapses in panel A are in the correlation distributions. C Average correlation between DSC and DFC over time for different sizes of the moving window. Shaded areas are SEM across neuron pairs. Left: DFC keeping delay consistency (i.e., measures computed only at previously estimated delay); Middle: DFC without delay consistency; Right: boost in correlation between DFC and DSC when keeping delay consistency (difference between left and middle panels)