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Table 2 Segmentation evaluations and comparisons

From: ID-Seg: an infant deep learning-based segmentation framework to improve limbic structure estimates

Dataset Metric Region Segmentation method F p.adj
   dHCP ID-Seg without pre-training ID-Seg with pre-training   
Internal dataset: ECHO-Dataset1 DSC L Amyg 0.79 (0.12) 0.76(0.07) 0.86(0.03) 8.81 0.001
(n = 20)   L Hippo 0.76 (0.09) 0.75 (0.08) 0.87 (0.03) 14.10  < 10−4
   R Amy 0.77 (0.14) 0.76 (0.08) 0.86 (0.03) 6.31 0.003
   R Hippo 0.74 (0.15) 0.76 (0.08) 0.87 (0.03) 10.67  < 10−4
  ICC L Amyg 0.87 (0.09) 0.86 (0.05) 0.92 (0.02) 3.41 0.05
   L Hippo 0.86 (0.08) 0.85 (0.06) 0.93 (0.02) 4.75 0.024
   R Amyg 0.86 (0.13) 0.86 (0.05) 0.92 (0.02) 3.79 0.05
   R Hippo 0.84 (0.13) 0.86 (0.05) 0.93 (0.01) 5.89 0.02
  ASD L Amyg 0.49 (0.34) 0.41 (0.09) 0.32 (0.11) 5.89 0.007
   L Hippo 0.60 (0.37) 0.61 (0.59) 0.26 (0.11) 10.38 0.001
   R Amyg 0.53 (0.47) 0.79 (1.3) 0.31 (0.09) 3.97 0.024
   R Hippo 0.65 (0.43) 0.66 (0.57) 0.26 (0.11) 6.43 0.006
External dataset: M-CRIB DSC L Amyg 0.73 (0.02) 0.81 (0.03) 0.88 (0.02) 184.47  < 10−4
(n = 10)   L Hippo 0.67 (0.04) 0.81 (0.03) 0.88 (0.03) 156.2  < 10−4
   R Amyg 0.67 (0.03) 0.83 (0.04) 0.87 (0.02) 68.78  < 10−4
   R Hippo 0.60 (0.04) 0.83 (0.03) 0.87 (0.03) 109.61  < 10−4
  ICC L Amyg 0.86 (0.05) 0.90 (0.01) 0.93(0.01) 195.48  < 10−4
   L Hippo 0.83 (0.06) 0.91 (0.02) 0.94(0.01) 393.73  < 10−4
   R Amyg 0.83 (0.06) 0.90 (0.02) 0.93(0.01) 88.13  < 10−4
   R Hippo 0.78 (0.09) 0.91 (0.01) 0.93(0.02) 373.74  < 10−4
  ASD L Amyg 0.94 (0.13) 0.55 (0.06) 0.36 (0.11) 190.95  < 10−4
   L Hippo 2.5 (0.29) 0.37 (0.17) 0.25 (0.06) 158.59  < 10−4
   R Amyg 1.1 (0.11) 0.45 (0.09) 0.41 (0.09) 70.13  < 10–4
   R Hippo 3.3 (0.44) 0.41 (0.18) 0.28 (0.06) 112.71  < 10–4
  1. DSC Dice similarity coefficients, ICC intra-class correlation, ASD average surface distance, measured in mm. Segmentation metrics for each method are shown in mean (standard deviation). Higher DSC and ICC, and lower ASD indicate better segmentation accuracy. Amyg Amygdala, Hippo hippocampus; L left; R right