Variations in structural MRI quality significantly impact commonly used measures of brain anatomy

Gilmore, Alysha D.; Buser, Nicholas J.; Hanson, Jamie L.

doi:10.1186/s40708-021-00128-2

Brain Informatics

Table 3 Relations between cortical thickness and structural MRI quality (as measured by the CAT12 Toolbox)

From: Variations in structural MRI quality significantly impact commonly used measures of brain anatomy

Area parcel	t_statistics	p_value	p_adjusted
lh_bankssts	1.08997	0.27700	0.40948
lh_caudalanteriorcingulate	− 1.34432	0.18032	0.29907
lh_caudalmiddlefrontal	4.30970	0.00003	0.00022
lh_cuneus	0.15952	0.87342	0.91373
lh_entorhinal	5.07313	0.00000	0.00001
lh_fusiform	2.68890	0.00776	0.02526
lh_inferiorparietal	2.74840	0.00652	0.02463
lh_inferiortemporal	2.60408	0.00988	0.03055
lh_isthmuscingulate	− 1.90339	0.05838	0.12807
lh_lateraloccipital	2.86879	0.00455	0.02062
lh_lateralorbitofrontal	2.02652	0.04400	0.10011
lh_lingual	− 1.65309	0.09983	0.18348
lh_medialorbitofrontal	− 0.23206	0.81673	0.88155
lh_middletemporal	2.26172	0.02476	0.06734
lh_parahippocampal	0.60225	0.54767	0.65336
lh_paracentral	1.85395	0.06518	0.13850
lh_parsopercularis	1.76791	0.07856	0.15382
lh_parsorbitalis	1.22890	0.22051	0.33322
lh_parstriangularis	1.00086	0.31807	0.45060
lh_pericalcarine	− 1.57667	0.11641	0.20831
lh_postcentral	1.76425	0.07917	0.15382
lh_posteriorcingulate	− 0.24391	0.80755	0.88155
lh_precentral	6.57110	0.00000	0.00000
lh_precuneus	0.61377	0.54005	0.65336
lh_rostralanteriorcingulate	− 1.52622	0.12849	0.21843
lh_rostralmiddlefrontal	− 0.18503	0.85339	0.90672
lh_superiorfrontal	1.77457	0.07745	0.15382
lh_superiorparietal	2.90099	0.00412	0.02058
lh_superiortemporal	4.18747	0.00004	0.00032
lh_supramarginal	3.78244	0.00020	0.00138
lh_frontalpole	− 1.29074	0.19824	0.30869
lh_temporalpole	5.46017	0.00000	0.00000
lh_transversetemporal	0.81222	0.41760	0.55680
lh_insula	0.97027	0.33305	0.46219
rh_bankssts	1.55943	0.12043	0.20998
rh_caudalanteriorcingulate	− 0.57201	0.56794	0.66586
rh_caudalmiddlefrontal	4.45687	0.00001	0.00013
rh_cuneus	0.89066	0.37415	0.50884
rh_entorhinal	5.28642	0.00000	0.00001
rh_fusiform	2.58405	0.01046	0.03091
rh_inferiorparietal	1.28643	0.19974	0.30869
rh_inferiortemporal	2.89207	0.00424	0.02058
rh_isthmuscingulate	− 2.20428	0.02861	0.07483
rh_lateraloccipital	2.78964	0.00577	0.02372
rh_lateralorbitofrontal	2.17463	0.03080	0.07756
rh_lingual	− 0.63065	0.52897	0.65336
rh_medialorbitofrontal	− 2.37653	0.01839	0.05211
rh_middletemporal	2.78051	0.00593	0.02372
rh_parahippocampal	2.02490	0.04417	0.10011
rh_paracentral	2.68693	0.00780	0.02526
rh_parsopercularis	2.71333	0.00722	0.02526
rh_parsorbitalis	0.12045	0.90424	0.91774
rh_parstriangularis	0.75355	0.45198	0.59105
rh_pericalcarine	− 0.14035	0.88852	0.91545
rh_postcentral	0.64465	0.51987	0.65336
rh_posteriorcingulate	− 1.05990	0.29043	0.42020
rh_precentral	5.57632	0.00000	0.00000
rh_precuneus	0.38736	0.69889	0.79208
rh_rostralanteriorcingulate	0.49376	0.62200	0.71688
rh_rostralmiddlefrontal	− 0.09858	0.92157	0.92157
rh_superiorfrontal	1.29407	0.19709	0.30869
rh_superiorparietal	2.97047	0.00333	0.02056
rh_superiortemporal	2.89752	0.00417	0.02058
rh_supramarginal	1.71206	0.08839	0.16696
rh_frontalpole	− 0.28271	0.77768	0.86692
rh_temporalpole	5.11553	0.00000	0.00001
rh_transversetemporal	2.07574	0.03916	0.09510
rh_insula	0.71959	0.47259	0.60635

Table displays relations between MRI quality (CAT12 score) and cortical thickness for different brain parcels in Freesurfer’s DK atlas. The left side of the table shows regions in the left hemisphere, while the right side shows the right hemisphere. On each side, region is in the first column, and t-statistic (of CAT12 and cortical thickness) is in the second column. The third column is the uncorrected p-value, while the fourth column is this test statistic corrected for multiple comparisons (for all 68 parcels). Italics highlighting indicates regions that were p < .05 (uncorrected), while bold indicates regions that were p < .05 (FDR corrected)

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