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Brain Informatics
Fig. 6 | Brain Informatics

Fig. 6

From: Deterioration from healthy to mild cognitive impairment and Alzheimer’s disease mirrored in corresponding loss of centrality in directed brain networks

Fig. 6

Middleman nodes L OFC (left) and LOC (right) with corresponding incoming and outgoing connections. From top to bottom: HC, EMCI, LMCI, AD. We can observe gradual pruning of the connections associated with these middleman nodes as the disease progresses from EMCI through AD. OFC orbito-frontal cortex, LOC lateral occipital cortex, LC locus coeruleus, SFG superior frontal gyrus, MFG middle frontal gyrus, IFG inferior frontal gyrus, PHG parahippocampal gyrus, MTG middle temporal gyrus, MOG middle occipital gyrus, Thal thalamus, LPS lateral parietal cortex, Ins insula

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