Fig. 1From: A structural equation model for imaging genetics using spatial transcriptomicsThe graphical structural equation model. Observed variables are shown in grey circles, latent variables in white circles, and error variables without circles. This example contains two latent variables, both with their own set of observed brain region measurements. This structure, where the latent variables define groups of region measurements, is defined by prior knowledge on these brain regions. We use spatially resolved gene expression data of the healthy human brain to define these region groupsBack to article page