Two-dimensional enrichment analysis for mining high-level imaging genetic associations

Brain Informatics

Table 2 Top enriched OMIM diseases of identified GSs

GS ID	# of gene	OMIM Disease	P value
GS01	81	Encephalopathy	4.2E\(-\)2*
		Dementia	3.6E\(-\)2*
GS02	168	Encephalopathy	5.0E\(-\)2
		Breast cancer	9.5E\(-\)2
GS03	55	Leukemia	2.7E\(-\)2*
		Alzheimer’s disease	8.9E\(-\)2
GS04	66	Hypertension	5.0E\(-\)2
GS05	19	Anomalies	2.4E\(-\)2*
		Alzheimer’s disease	4.5E\(-\)2*
GS06	28	Ectodermal dysplasia	2.0E\(-\)2*
GS07	24	Hypertension	3.4E\(-\)2*
		Spinocerebellar ataxia	4.3E\(-\)2^*
GS08	33	Glycogen storage disease	1.6E\(-\)2*
GS09	111	Immunodeficiency	1.4E\(-\)2*