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Table 1 Relation types from (a) the BioNLP shared task 2011 and (b) identified during the relation annotation process by our medical expert

From: An adaptive annotation approach for biomedical entity and relation recognition

 

Descriptions

(a) Relation types from BioNLP 2011

 Equivalent

Two protein or cell components are equivalent

 Protein-component

The protein-component is a less specific object-component relation that holds between a gene or protein and its component, such as a protein domain or the promoter of a gene.

 Subunit-complex

Subunit-complex is a component-object relation that holds between a protein complex and its subunits, individual proteins

(b) New relation types

 Activator-reactor

Two proteins linked with the same reaction; the first one is responsible for starting the reaction and the second one responsible for its sustainability

 Antibody–antigen

An immune protein with the ability to specifically bound the antigen, a foreign substance, and to neutralise its toxicity

 Cell-marker

A set of surface proteins typical for a cell lineage or a stage of development

 Cell-variant

The main cell lineage and the subtypes which are the parts of this larger cell family

 DNA-transcript

DNA and its mRNA (messenger RNA) which translate the gene‘s message to a protein product

 Ligand–receptor

Two proteins or molecules which can bind to each other because oft he complementarity of the binding site

 Protein-variant

Two proteins with the similar structure and function