Table 3 Short descriptions for the largest clusters
Cluster ID | Clinical status | Biological properties (with z score versus cognitive normal) | |
|---|---|---|---|
Clusters for female patients | |||
F1 | Significant cognitive problems (high ADAS13, high FAQ, high MMSE) | Low FDG | 9.29 |
Low entorhinal | 8.74 | ||
High AV45 | 8.36 | ||
Low hippocampus | 8.33 | ||
Low MidTemp | 7.52 | ||
Low fusiform | 7.13 | ||
High TAU | 7.12 | ||
F0 | Mild or no dementia | High FDG | 6.05 |
High hippocampus | 2.86 | ||
High whole brain | 2.85 | ||
Clusters for male patients | |||
M1 | Significant cognitive problems | Low FDG | 8.23 |
Low hippocampus | 7.70 | ||
Low entorhinal | 7.09 | ||
Low MidTemp | 6.33 | ||
Low whole brain | 6.23 | ||
High TAU | 5.57 | ||
M2 | Significant cognitive problems | Low FDG | 7.83 |
High ICV | 6.54 | ||
High ventricles | 5.70 | ||
Low hippocampus | 5.60 | ||
Low ABETA | 5.80 | ||
M0A | Mild or no dementia | High FDG | 4.98 |
High ICV | 4.00 | ||
High whole brain | 3.31 | ||
M0B | Mild or no dementia | Low ICV | 4.83 |
Low whole brain | 3.74 | ||